Which action by the nurse while administering human growth hormone ensures effective therapy?

Which action by the nurse while administering human growth hormone ensures effective therapy?

• A. Administration at nighttime
• B. Administration via oral route
• C. Administration along with meals
• D. Administration by metered spray

Answer: (A)

Growth hormone therapy works best when the dosing mirrors the body’s natural pattern, which is a pulse of GH release during sleep. Administering it at nighttime aligns with this nocturnal surge, letting the hormone act when the body is most receptive and during the fasting state, enhancing growth-promoting and metabolic effects. Oral administration would destroy the protein in the digestive tract, making it ineffective; taking it with meals would reduce absorption; a metered nasal spray isn’t a reliable or standard method for GH delivery. So nighttime administration best supports the therapy’s effectiveness.