NCLEX Endocrine System Practice Test

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• A client with Addison's disease commonly presents with which classic sign?
• Why must potassium be monitored closely during DKA treatment?
• In screening for an endocrine tumor causing hypertension, which test measures metabolites of catecholamines?
• During the menstrual phase, which layer of the endometrium is shed?
• Which statement best describes the thyroid function pattern in autoimmune Hashimoto thyroiditis?
• A malnourished client with cirrhosis presents with nausea, ascites, and GI bleeding. What is the primary cause of the ascites?
• What are common signs of hypoparathyroidism after thyroidectomy?
• PTH action in the kidney occurs in which nephron segment to increase calcium reabsorption?
• Which hormone regulates blood levels of calcium?
• Which electrolyte disturbance is commonly seen in Addison's disease?
• Approximately on which cycle days does the LH surge occur?
• Which statement best describes A1C testing in the management of diabetes?
• What is the clinical significance of TSH receptor antibodies?
• What is the primary treatment approach for SIADH?
• Which condition results from excessive secretion of antidiuretic hormone?
• After resection of an aldosterone-secreting adrenal tumor, which statement best reflects the patient’s prognosis and return-to-work potential?
• Which hormone is a classic example of positive feedback in the female reproductive system?
• Which hormone surge triggers ovulation?
• Which nursing intervention is part of care after unilateral adrenalectomy?
• What is the role of calcitonin in calcium homeostasis?
• For a 24-hour urine vanillylmandelic acid test to help confirm pheochromocytoma, which instruction should the nurse include?
• Desmopressin is a synthetic analog of which hormone?
• In diabetes mellitus, vision changes are caused by which process in the retina?
• Which of the following statements best describes the lab pattern in primary hypothyroidism?
• A hospitalized client with a tentative pancreatic cancer diagnosis asks the nurse for reassurance. What is the best reply?
• Which calcium value would best support the diagnosis of parathyroid dysfunction as described in the clinical scenario?
• Which statement about Graves' disease is true?
• Which endometrial layer regenerates to rebuild the functional layer after menses?
• During ADH stimulation testing, which action demonstrates proper safety preparation?
• Which condition is defined by kidney insensitivity to ADH, leading to polyuria?
• How do you differentiate primary from secondary hypothyroidism using labs?
• Which statement should the nurse include when teaching a client with type 2 diabetes who will take oral antidiabetic medications about glucose monitoring?
• Which condition is treated with desmopressin (DDAVP)?
• Which pituitary hormone is deficient in central diabetes insipidus?
• Which hormone is primarily responsible for triggering ovulation via its surge?
• Besides progesterone, which hormone is also produced by the corpus luteum to support the endometrium early in pregnancy?
• What are typical signs of diabetes insipidus?
• What is a key nursing intervention for SIADH?
• Which feature indicates hypersecretion of adrenocorticotropic hormone?
• If severe hypercalcemia persists after hydration, which adjunct therapy may be used?
• Which combination of signs is classic for Cushing syndrome?
• To ensure an accurate urine endocrine test result, which instruction should the nurse provide?
• Which hormone level peaks during sleep?
• In autoimmune Hashimoto thyroiditis, what hormone deficiency is primary?
• What is the mechanism of action of methimazole in hyperthyroidism?
• Which metabolic manifestations are likely to be observed in a client with hypothyroidism? (Choose the most characteristic symptom from the list below.)
• Which gland is stimulated by corticotropin-releasing hormone from the hypothalamus to release cortisol?
• Calcitonin lowers serum calcium by inhibiting which bone cell activity?
• The described signs are most consistent with which disorder?
• Starting levothyroxine in older adults requires caution due to potential risk of which complication?
• Calcitonin's effect on calcium homeostasis primarily involves which tissue?
• Which hormone is secreted by the hypothalamus to stimulate the pituitary gland to release ACTH?
• What is the most common cause of Cushing syndrome?
• Which brain region is responsible for secreting gonadotropin-releasing hormone?
• Which condition is characterized by polyuria with low urine osmolality?
• What A1C level is generally considered a good target for many nonpregnant adults?
• Which condition is characterized by hyponatremia and hyperkalemia?
• When initiating levothyroxine in older adults, what is the recommended approach?
• Where is fertilization most likely to occur?
• Which gland is the source of parathyroid hormone (PTH)?
• Which statement NOT a typical sign of hyperfunctional thyroid?
• What is the primary action of parathyroid hormone (PTH) on the kidneys?
• Which organ produces parathormone?
• What should be assessed after thyroidectomy?
• What is metformin's primary action in type 2 diabetes?
• Which diagnostic study is most appropriate to confirm autoimmune thyroiditis in a postpartum patient?
• A nurse is caring for a client with Cushing syndrome. Which clinical manifestation is commonly associated with this condition?
• Which medication is beneficial for acromegaly?
• What trio is typically present in diabetic ketoacidosis?
• The luteal phase of the menstrual cycle occurs on which days?
• In a client with long-standing type 1 diabetes and poor past management, which finding is most likely to be identified during assessment?
• Pretibial myxedema is associated with which condition?
• Which condition is most likely to require fluid restriction as part of its management?
• If fertilization does not occur, the corpus luteum degenerates into which structure?
• Which statement is true regarding cortisol?
• After thyroidectomy, tingling or cramps are most likely signs of which electrolyte disturbance?
• Which hormone is produced synthetically for replacement therapy in hypothyroidism?
• Which clinical indicator should the nurse identify as expected for a client with type 2 diabetes?
• After total thyroidectomy, which instruction is most important for the client to follow?
• Levothyroxine replacement therapy provides which form of thyroid hormone?
• What monitoring is essential for a patient on a continuous insulin infusion?
• What electrolyte disturbances are common in Addison's disease?
• Which laboratory test will be most beneficial in monitoring the effectiveness of drug therapy for hyperthyroidism?
• Which is NOT a typical sign of hyperfunctional thyroid?
• An older adult with a history of small cell lung carcinoma reports muscle cramping, thirst, and fatigue. The primary healthcare provider diagnoses the client with a pituitary disorder and is treating the client accordingly. Which is an effective outcome of the treatment?
• If a patient with diabetes is at goal on A1C testing, how often is testing typically performed?
• The client's pituitary gland must be removed. Which surgery will the client undergo?
• Which hormone is primarily secreted by the corpus luteum to support early pregnancy?
• A patient who has undergone nasal hypophysectomy shows a nasal discharge. Which sign indicates cerebrospinal leakage?
• In a patient with type 2 diabetes who has insulin and glyburide ordered, the nurse should take which initial action when a discrepancy in timing is noted?
• A client with adrenal insufficiency is prescribed fludrocortisone. Which nursing action minimizes risk of a potential side effect?
• A client starting continuous ambulatory peritoneal dialysis asks what it entails. Which statement is correct?
• In the RAAS sequence, which event occurs immediately after angiotensinogen is converted to angiotensin I?
• In primary hypothyroidism, what pattern is typically seen in TSH and free T4?
• Which of the following findings is typically associated with hyperthyroidism?
• Which finding is most commonly associated with Graves disease?
• The follicle’s release of estrogen leads to which hormonal surge?
• What is the normal serum calcium range?
• Which sign might indicate worsening hyponatremia in SIADH?
• Which activity would most likely increase intracranial pressure in a patient who had a hypophysectomy?
• After total thyroidectomy, which hormone is required for lifelong replacement therapy?
• Which endocrine emergency is described by severe tachycardia, hyperthermia, and altered mental status and requires immediate treatment?
• In the management of Addison disease, which statement best reflects the main treatment goal?
• The laboratory reports of a client who underwent a hypophysectomy show an intracranial pressure (ICP) of 20 mmHg. Which action made by the client is responsible for this condition?
• Which symptom would best indicate Cushing's syndrome in a patient with suspected hypercortisolism?
• In a typical 28-day menstrual cycle, the follicular phase occurs during which days?
• The laboratory report of a pregnant client shows increased adrenocorticotropic hormone, salivary cortisol, and blood glucose levels. What should the primary healthcare provider instruct the nurse to include in the plan of care for the client to help reduce the risk of death in the client?
• Which gland primarily regulates basal metabolic rate?
• During growth hormone therapy, which timing is most effective for administration?
• Which cardiac manifestation is commonly seen in hyperthyroidism?
• After surgical clipping of a cerebral aneurysm, a client develops SIADH. Which manifestation is most consistent with excessive ADH?
• Diabetes insipidus results from deficiency or resistance to which hormone?
• Which phase is characterized by endometrial thickening in preparation for potential implantation?
• What is a classic sign of Graves' disease?
• What is a hallmark feature of thyroid storm?
• Which clinical manifestations would a client with newly diagnosed type 1 diabetes most likely report during a health history?
• Which combination of findings is most reminiscent of a thyroid storm?
• A nurse explains the cause of diabetic ketoacidosis in diabetes. Which of the following best describes the primary metabolic process?
• Which foods are excellent sources of both vitamin E and beta-carotene?
• Which action by the nurse while administering human growth hormone ensures effective therapy?
• What is a common cause of nephrogenic diabetes insipidus?
• Which statement is NOT a function of progesterone and estrogen in the menstrual cycle?
• Which laboratory pattern characterizes diabetic ketoacidosis?
• Which statement describes subtotal thyroidectomy?
• Which insulin type has the fastest onset of action?
• Which hormone is secreted by the posterior pituitary and promotes water reabsorption in the kidneys?
• Which pattern of thyroid function tests is typical in autoimmune Hashimoto thyroiditis?
• Which finding is most commonly associated with hyperthyroidism?
• Which of the following statements would best describe the expected status in a patient who has followed the prescribed diabetes treatment plan?
• Which symptom is most consistent with hyperthyroidism?
• Which test should be used to help confirm pheochromocytoma?
• Which of the following is a recognized sign of a stress ulcer in a hospitalized patient?
• What is the immediate treatment priority in myxedema coma?
• In a client with Cushing syndrome, why is there concern for developing diabetes mellitus?
• Which feature is characteristic of acromegaly after adjusting options?
• Which laboratory test is most beneficial to monitor the effectiveness of hyperthyroidism drug therapy?
• Which symptoms are typical at presentation of type 1 diabetes mellitus?
• Central diabetes insipidus is due to impaired production of which hormone?
• What is the immediate management for severe hypoglycemia with altered mental status?
• Which finding would indicate the need to adjust hydrocortisone dosage in a patient with adrenal hypofunction?
• Which drugs are PTU and methimazole used for?
• What is the typical duration of the luteal phase?
• Hyperosmolar hyperglycemic state commonly presents in which patient population?
• Ovulation is typically around which day in a standard 28-day cycle?
• In a typical 28-day cycle, the most fertile days occur during which days?
• A client is diagnosed with parathyroid dysfunction. Which serum calcium concentration would support the diagnosis?
• Which study will the nurse prepare to monitor that best screens for an endocrine tumor presenting with hypertension?
• A primary healthcare provider writes prescriptions addressing the needs of a client with Addison disease. Which outcome does the nurse conclude is the main focus of treatment for this client?
• Which statement best describes the symptom profile commonly associated with hypothyroidism?
• What is an initial management step for severe hypercalcemia?
• Which sign is associated with hypocalcemia?
• Which statement best helps a family understand mood changes associated with Cushing syndrome?
• A client with newly diagnosed diabetes refuses asparagus, broccoli, and mushrooms. Which substitutions on the food exchange list would be appropriate to replace these choices?
• A glycosylated hemoglobin measurement of 6%. What should the nurse conclude about this client when planning teaching strategies based on the results of this laboratory test?
• Which hormone is secreted by the pancreas and helps regulate blood glucose levels?
• What are common signs of hyperthyroidism?
• What is typically elevated in hyperparathyroidism?
• What is a common long-term risk after radioactive iodine therapy for hyperthyroidism?
• The gland that secretes gonadotropin-releasing hormone is which part of the brain?
• Which statement best describes the laboratory pattern in autoimmune hypothyroidism?
• Before a brain CT with contrast, which nursing finding should be reported to the physician?
• For a patient using an insulin pump, which education is essential to cover?
• Which symptom most clearly indicates hyperglycemia in a person with diabetes?
• Which statement best describes the ovulation phase regarding basal body temperature?
• In which phase does the corpus luteum form?
• Placental takeover of hormone production occurs at approximately which gestational age?
• What does A1C measure and how often should it be checked?
• How does hyperosmolar hyperglycemic state (HHS) typically present?
• How is hyperparathyroidism typically manifested in labs?
• Which preoperative instruction is appropriate for a patient scheduled for thyroidectomy?
• A nurse is assessing a client suspected of having hypercortisolism. Which question would help confirm the diagnosis?
• Which hormone increases hepatic glucose production and is commonly elevated during stress?
• Which sign is commonly associated with Graves' disease?
• For a hyperactive thyroid workup including protein-bound iodine, T3, and T4 tests, what should the nurse verify to ensure accurate results?
• What is the effect of desmopressin in DI management?
• About how much dialysate is typically maintained in the peritoneal cavity during CAPD?
• What distinguishes secondary hypothyroidism from primary on lab testing?
• Which cycle day range corresponds to the proliferative stage?
• Which urine characteristic is typical in SIADH?
• Which statement about progesterone is correct?
• In a patient with a pituitary disorder being treated for fluid balance, which urine finding would indicate improved concentrating ability?
• Which hormone is produced by the adrenal cortex and plays a key role in metabolism and the stress response?
• During ovulation, the ovum is released into which part of the female reproductive tract?
• Which hormone from the anterior pituitary stimulates the maturation of ovarian follicles?
• Which gland secretes cortisol?
• Arrange the series of reactions that occurs when plasma volume and osmolarity are disturbed.
• What is the initial treatment for suspected adrenal crisis?
• What is a major nursing consideration for a client with hyperthyroidism during hospitalization?
• What is the most common presenting symptom of hypothyroidism?
• Endometrium thickening is most closely associated with which menstrual cycle phase?
• During which cycle days does the proliferative stage occur?
• Which physiologic response should be expected in hyperthyroidism?
• What are signs of thyrotoxicosis?
• An individual with Addison disease is emaciated and fatigued. Which disturbed body process is the root cause of these manifestations?